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Rheumatoid factor

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This test is most often used to diagnose rheumatoid arthritis. About 80% of patients with rheumatoid arthritis have positive RF tests.

But the RF test may also be positive in healthy people.

 

RF is an antibody that attaches to a substance called immunoglobulin, forming an immune complex. The immune complex can trigger different types of inflammation-related processes.

 

A positive test may be due to:

  • Chronic hepatitis
  • Chronic viral infection
  • Dermatomyositis
  • Infectious mononucleosis
  • Leukemia
  • Rheumatoid arthritis
  • Scleroderma
  • Systemic lupus erythematosus
  •  Adult Still's disease
  • Juvenile rheumatoid arthritis
  • Nephrotic syndrome
  • Sjogren syndrome

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