can also find a more technical version of ANA testing in TEST.
I cannot stress enough that the results of an ANA test is NO indication that you
have lupus. It is not a good indicator that your lupus has increased or decreased its activity.
ANA is a tool for your physician.
ANA reports include a titer (number) and a pattern. ANA titers go up and down during the course of illness,
age and other disease.
An ANA or FANA test can even be weakly positive in healthy individuals. The chances
of a person having a positive ANA test increases with age.
(What disease and
or any disease activity are best left to doctors to decide.)
A titer of between the reference ranges of 1:80 and 1:160 is considered, in most laboratory test, to be within
a normal range. Because of how it is determined, a 1:640 shows a greater concentration of anti-nuclear
antibodies than a titer of 1:320 or 1:160.
The patterns found in ANA are another indicator for your doctor.
A person may have a smooth pattern, a speckled pattern, a rim pattern (found almost exclusively in SLE) or
a nucleolar pattern.
The homogeneous (smooth) pattern
is found in a variety of connective tissue diseases, some rheumatic diseases, or in patients taking
The speckled pattern is found
in mainly in other connective tissue diseases or autoimmune diseases, while the peripheral (or rim) pattern is found almost exclusively in SLE.
The nucleolar (a pattern with
a few large spots) pattern is found primarily in patients with scleroderma.
A titer ABOVE 1:80 which is usually considered positive disease activity and a peripheral pattern titer are usually suspect of Lupus